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In a clinical study involving 40 female participants over 28 days, PAPE achieved up to 34% wrinkle reduction when applied twice-daily for four weeks.
Biotech R&D company ApiotiX Technologies, headquartered in Croatia, has published a clinical study in the Journal of Cosmetic Dermatology of the anti-wrinkle efficacy of its patented standardized phenolic acids polymer extract (PAPE) from propolis. “Our evidence-based solutions with a defined mode of action make PAPE a promising addition to skincare,” said Dr. Bozo Radic, chief operating officer, ApiotiX Technologies. “In vitro studies indicated that PAPE could modulate inflammat...
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